Abstract Background After viral fusion with the cell membrane, the conical capsid of HIV-1 disassembles by a process called uncoating.Previously we have utilized the CsA washout assay, in which TRIM-CypA mediated restriction of viral replication is used to detect the state of the viral capsid, to study the kinetics of HIV-1 uncoating in owl monkey
Abstract Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide.Despite its high prevalence, effective treatment strategies for TBI are limited.Traumatic brain injury induces structural and functional alterations of astrocytes, the most abundant cell type in the brain.As a way of coping with the trauma, astro
Existing reinforced concrete (RC) buildings in Europe have generally been designed without proper consideration of seismic actions and capacity design principles, and thus they tend to be vulnerable to earthquakes.Moreover, since a significant proportion of the aforementioned buildings were developed during the 1950s and 1960s, they are Window Hard